Injectable filler is a soft tissue filler injected into the skin to help fill in facial wrinkles, restoring a smoother appearance. Most fillers are temporary, lasting anywhere from six months to a year. There are different kinds: Juvederm, Restylane and Perlane. Juvaderm Voluma has been clinically proven to last up to two years. All fillers are temporary because they are eventually absorbed by the body.